Slope Resources

Discover how the University of Arizona Cancer Center (UACC) transformed its clinical trials operations by cutting scheduled test deviations by 44%. This case study reveals how UACC overcame significant inventory management challenges that impacted trial safety, efficacy, and patient experience. Through the adoption of Slope’s clinical inventory management software, UACC streamlined workflows, ensured timely patient assessments, and enhanced their reputation with trial sponsors—all while improving patient satisfaction.

Teal Health, aiming to revolutionize women's healthcare with their at-home cervical cancer screening device, the Teal Wand™, faced significant challenges during their initial clinical trials. These challenges included manual inventory and sample tracking, handwritten shipping manifests, and scaling issues as they expanded from a small pilot to a larger pivotal study.

Upgrading from disparate manual processes to a unified digital platform for managing inventory, Gabrail Cancer Center was able to reclaim hours of staff time each week, reduce lab kit waste by more than 20% across all of its studies, and enhance its collaboration with study stakeholders.

As an epicenter for clinical research in the Mid-Atlantic, this large, world-renowned academic medical center (AMC) is a bustling hub for lab kits and other supplies. The dilemma, however, was that they did not have an efficient logistical infrastructure to support the high volume of inventory that was circulating through their disease centers. Leveraging a centralized, comprehensive inventory management platform translated to better accountability of lab kits, waste prevention, and more informed decision-making.

This emerging biotech was facing operational difficulties within its Phase 1 Oncology programs because of its complicated designs and sample requirements. Each study had an intricate network of clinical sites, a detailed clinical sample schema, multiple external sample destinations, and required shipping conditions. This was compounded by economic pressures and supply chain inefficiencies during the COVID pandemic. Read the case study to learn how this organization saved over $300k by leveraging Slope's clinical trial execution platform.

As precision medicine demands more complex study designs, static lab manuals and traditional methods for biospecimen management introduce serious risks. This white paper sheds light on the lab manual’s current role in sample management, the inherent pitfalls of traditional approaches, and the ways in which sponsors can leverage technological innovations to standardize research site practices and optimize compliance across all of their trials.

Oncology clinical trial participants are required to contribute various biological samples — such as blood, saliva, and tissue — to demonstrate how a study drug could potentially affect their disease.

A site-centric clinical trial execution platform for managing inventory and biospecimens can dramatically improve compliance, efficiency, and visibility to the entire sample journey. This white paper sheds light on the lab manual’s current role in sample management, the inherent risks and challenges with traditional approaches, and the ways in which research sites can leverage technological innovations to completely revamp their operations across all of their studies.

Sponsors who are at the helm of clinical trial operations are responsible for crafting a robust monitoring strategy for every clinical trial. Part of their mission is to implement plans and solutions that safeguard patient well-being, ensure the accuracy and completeness of trial data, and facilitate compliance with both currently approved study documents and regulatory requirements.The reality is that the modern landscape of clinical research makes monitoring a daunting task. This e-book explores the ways in which you can optimize your clinical trial monitoring strategy to boost research site compliance.

Slope’s inaugural State of Clinical Inventory and Sample Management survey gathered insights from 146 biopharma professionals on the impacts of inefficient, manual processes for managing clinical supply — lab kits, devices, ancillary supplies, and investigational product (IP) — and samples on budgets, timelines, data integrity, and patients. The survey findings highlight the pain felt by study teams as the complexity of the supply chain is not supported by standardized processes and technology. There is an acknowledgment of the problem, and yet most have not transformed the way they are operationalizing their clinical trials to address it. The existing processes currently in place are incapable of ensuring the availability of crucial clinical inventory, including lab kits, drugs, devices, and other essential supplies. Moreover, there is a significant lack of transparency regarding the biospecimen chain of custody. This lack of visibility leads to various negative consequences, such as delays in studies, reduced trial outcomes, exceeded budget limits, and most importantly, a direct impact to the performance of research sites and the well-being of their patients.

Slope is a global provider of biospecimen lifecycle software, data, and services for clinical trials. With a focus on tech-enabling the full biospecimen lifecycle, Slope offers expertise that empowers sponsors to make informed decisions using high-quality, real-time sample data. Slope has supported thousands of the most complex, sample-intensive trials worldwide and has been adopted by the vast majority of NCI-designated cancer centers. Download our brochure to learn more.

Learn more about how Slope can help your investigator-initiated trials achieve compliance, reduce study deviations, and streamline workflows with affordable, tech-enabled solutions. Discover how real-time sample tracking, automated inventory management, and expert support can save your team time and resources while maintaining research integrity across single-center and multi-center trials.

Discover how Slope’s Biospecimen360™ software and services go beyond traditional point solutions to support the entire biospecimen lifecycle — from inventory management and sample tracking to comprehensive sample metadata management. Download now to see how Slope compares to other systems and service providers.

Take control of your biospecimen management with Slope's Biospecimen360™ comprehensive sofware platform.

Download our guide, "10 Ways to Optimize Your Biospecimen Operations", to discover essential strategies for addressing the most common challenges in biospecimen management

Ensure the success of your clinical trials with Slope’s comprehensive Professional Services, designed to optimize lab, biospecimen, and data management from start to finish. With expert support in protocol design, vendor selection, sample tracking, and data management, Slope empowers sponsors to meet critical timelines while maintaining data integrity and compliance. From study startup to closeout, Slope’s services provide oversight and monitoring at every stage, ensuring seamless trial execution and achieving your trial objectives with confidence.

Sponsors recognize that successful end-to-end sample management is crucial to developing new therapies, but the growth in clinical research — combined with increasing complexity of study designs — has exacerbated inconsistent and outdated approaches to sample management.

Slope transforms study execution by connecting systems and study stakeholders to direct site operations and drive real-time, traceable, and operational clinical data. By syncing information across vendors and eClinical systems including EDC, IRT, LIMS, shippers, and other systems, critical data surrounding inventory and sample management becomes accessible and actionable anytime — strengthening data integrity, empowering decision-making, and accelerating clinical research timelines.

Slope's inaugural State of Clinical Inventory and Sample Management survey gathered insights from 146 biopharma professionals on the impacts of inefficient, manual processes for managing clinical supply — lab kits, devices, ancillary supplies, and investigational product (IP) — and samples on budgets, timelines, data integrity, and patients. Download the survey report to learn more about these surprising findings.

Requisition forms have long been essential for sample management in clinical trials, but they also introduce inefficiencies, inconsistencies, and unnecessary complexity. Whether you’re optimizing existing processes or exploring new approaches, this guide will help you rethink requisition workflows for the modern era.

The updated ICH E6(R3) guidelines emphasize risk-based quality management, robust data governance, and enhanced oversight— placing greater accountability on sponsors and directly affecting the processes that govern samples and their associated data. For teams managing biospecimens, these changes raise the stakes for data integrity, sample traceability, and regulatory compliance. Slope’s Biospecimen360™ (B360™) software and professional services are designed to help you meet these evolving requirements with confidence. Download our guide to learn more.

Biospecimen360™ enhances efficiency, compliance, and data integrity across the biospecimen lifecycle — but what does that mean for your trial? This guide walks you through assessing your current study metrics to uncover where B360™ can help you reduce lab kit waste, maximize sample integrity, improve oversight, streamline data reconciliation, and more. Download now to see the measurable impact B360™ can have on your trials.

It goes without saying that patient samples are the backbone of clinical trials, but what does that really mean? These biospecimens provide the data that sponsors need in order to determine the safety and efficacy of potentially life-saving, life-changing treatments. Just as important, however, the patient samples that support clinical research are physical extensions of real people who oftentimes already find themselves in a vulnerable state because of disease. Treating their biospecimens with extreme care not only optimizes and accelerates study outcomes; it’s also an act of respect towards those who are already sacrificing so much of themselves by participating in a trial.

A risk-based monitoring strategy, coupled with comprehensive oversight of patient samples, is critical to biosample operations. What can sponsors do to prevent and mitigate common site compliance issues that hinder study milestones and outcomes?

As a sponsor, you face numerous obligations when executing clinical trials, with the primary goal of gathering sufficient data to demonstrate the safety and efficacy of investigational products or devices. The data you collect must be defensible and complete, and biological samples represent a critical source of that data. Therefore, to successfully execute a clinical trial, the sample management process also needs to be defensible and complete. It is crucial to have visibility into the entire sample journey, as it demonstrates protocol compliance and sample traceability. Lost or mishandled samples can significantly impact research sites, patients, data integrity, and study timelines.

As clinical researchers, your first responsibility is running your clinic and treating your patients You care that supplies are available for your patients and that critical safety, efficacy, and exploratory lab samples get where they need to be. You understand the impact of lost or invalid samples on the patient and the repercussions improper sample management has on the safety and efficacy data and the overall integrity of your study.

Alex Yant is a Solutions Engineer for Slope, the industry’s first Clinical Trial Execution platform. He works to add order, trust, and predictability to your clinical research trials, so they end on-time and on-budget. Alex has four years of healthcare experience, as both clinical research professional and a direct service provider. He holds a bachelor’s degree from the University of Wisconsin-Madison, and a Master of Science in Occupational Therapy from the University of Illinois at Chicago. In this episode we discuss the significance of diversity of experience in clinical trials, the role of sites in clinical trial inefficiency, and the complexity of managing site lab inventory.

Ethan Seville is a clinical research professional who has worked in a wide range of indications across various roles such as patient recruitment, coordinating, quality assurance, management, and regulatory. Ethan is now the Manger of Customer Engagement and Strategic Solutions for Slope.io, which helps researchers by ensuring their network of clinical trial patients get the exact medical supplies their care requires on time, on schedule and on budget. In this episode, Ethan interviews Brad.